The NSRC's parent organizations, the Smithsonian Institution and the National Academies further the NSRC programs through facilities support and the work of curators, science specialists, researchers, scientists, and others. These organizations may also help host NSRC advisory board gatherings and other vital meetings.

• National Museum of American History
• National Museum of Natural History
• National Air and Space Museum and Udvar Hazy Center
• National Museum of the American Indian
• Smithsonian Freer/Sackler Gallery
• Smithsonian Castle
• Smithsonian National Zoo
  • Zoo Conservation Research Center
• Smithsonian Enviromental Research Center (SERC)
• Smithsonian Center for Education and Museum Studies
• The National Academies Marian Koshland Science Museum

The National Science Resources Center (NSRC) also collaborates with regional museums and scientific facilites for programmatic work.

• NASA Goddard Space Flight Center
• B & O Railroad Museum, Baltimore
• The Historical Electronics Museum in Linthicum, MD
• National Institute of Standards and Technology
• Carnegie Institution for Science